





The advantages of the tablet dosage form are:
1. They are unit dosage form and offer the greatest capabilities of all oral dosage form for the greatest dose precision and the least content variability.
2. Cost is lowest of all oral dosage form.
3. Lighter and compact.
4. Easiest and cheapest to package and strip.
5. Easy to swallowing with least tendency for hang‐up.
6. Sustained release product is possible by enteric coating.
7. Objectionable odour and bitter taste can be masked by coating technique.
8. Suitable for large scale production.
9. Greatest chemical and microbial stability over all oral dosage form.
10. Product identification is easy and rapid requiring no additional steps when employing an embossed and/or monogrammed punch face.
Disadvantages of tablet dosage form are:
1. Difficult to swallow in case of children and unconscious patients.
2. Some drugs resist compression into dense compacts, owing to amorphous nature, low density character.
3. Drugs with poor wetting, slow dissolution properties, optimum absorption high in GIT may be difficult to formulate or manufacture as a tablet that will still provide adequate or full drug bioavailability.
4. Bitter testing drugs, drugs with an objectionable odor or drugs that are sensitive to oxygen may require encapsulation or coating. In such cases, capsule may offer the best and lowest cost.
More and more people are choosing Fish oil as a health product, but in the process of buying it, many consumers still have many questions about how to get the real deal and good quality Fish oil. Here, we would like to introduce you to a few ways to choose Fish oil. How do we choose?
This is the list of contents:
·Look at the origin
·Selecting raw materials
·Look at the appearance
·Smell
·Look at the certification mark
·Low-temperature test
Fish that live in the northern hemisphere generally have more w-3 fatty acids in their bodies, while fish from the southern hemisphere is relatively lean. Currently, the only two areas with the best-preserved natural environment are the Lower Norwegian Sea to the Barents Sea and the Labrador Sea, which naturally produce the highest quality Fish oils. Other regions, such as Australia and New Zealand, are over-exploited due to tourism, so the quality of Fish oil has also been affected to some extent.
Small fish at the bottom of the food chain usually contains fewer contaminants, while larger fish at the top of the food chain accumulate more toxins, so the best sources of Fish oil are small fish such as sardines, rather than salmon, mackerel, seals, etc.
Good Fish oil capsules are uniform in size and free from impurities. Good quality Fish oil capsules should be on the softer side and have no coloring agents added. They are pale yellow, crystal clear and have a very good body, and are not cloudy. A soft Fish oil capsule will not get stuck in the throat and is a better experience, while those capsules that are large and hard are often difficult to swallow and even require the capsule to be broken to pour out the Fish oil before it can be taken.
It is normal for Fish oil capsules to have a slight fishy smell, but if it smells heavy and feels a little top-heavy, it means that there is a problem with the quality and it is likely to be oxidized and spoilt.
If the product has a blue cap, it means that the quality of the product and the efficacy claimed on the packaging are recognized by the state and can be purchased with confidence.
Good Fish oil with a high proportion of EPA and DHA will not condense easily and will quickly return to a liquid state at room temperature, even if it condenses into a solid-state in extremely cold conditions, whereas a Fish oil with a low proportion of EPA and DHA will take longer to return to a liquid state. Therefore, to distinguish between good and bad Fish oil, the first Fish oil to return to liquid form after condensing in the freezer is the one with the highest purity of EPA and DHA.
These are just a few suggestions on how to buy Fish oil for reference. I believe that through this small science, we all have a certain understanding of how to select Fish oil. I hope that in the future when you choose Fish oil products, you can refer to the above six suggestions and buy safe, high-quality Fish oil products to protect the health of your family and friends!
They can be divided in to desired dosage strength without process or formulation changes.
When pellets containing the active ingredient are in the form of suspension, capsules, or disintegrating tablets, they offer significant therapeutic advantages over single unit dosage forms.
They can also be blended to deliver incompatible bioactive agents.
They can also be used to provide different release profile at the same or different sites in the gastrointestinal tract.
Pellets offer high degree of flexibility in the design and development of oral dosage form like suspension,sachet, tablet and capsule.
Pellets disperse freely in gastro intestinal tract (GIT), maximize drug absorption, and minimize local irritation of the mucosa by certain irritant drugs.
Improved flow characteristics: Spheres have excellent flow properties, which can be used in automated processes or in processes where exact dosing is required, e.g. tableting, moulding operations, capsule filling, and packaging.
Coating: Coating of granules is often applied for stabilizing active ingredients in the granule or to control the release of these active ingredients. Typical applications in the pharmaceutical industry are the controlled release medicines. The easiest shape to coat is the sphere due to the absence of edges. It is also the most economical one to coat as no extra coating material is required to fill irregularities in the surface of the granules.
Packing of beds and columns: In certain processes, porous beds or columns are used as chemical reactors. Spherical particles allow the reproduction of beds withalways the same void volume, surface area and permeability. Calculations and predictions of the process characteristics also become easier when round particles are used as many equations are based on flows around symmetrical bodies.
Density increase: Both the true and the bulk density of granules are increased by spheronising. This can improve the process and the packaging.
Marketing: For consumer products, spheronising is sometimes only applied for improved product appearance and marketing reasons.
Hardness and friability: Hardness and friability depend on the internal cohesive forces and surface characteristics. Spheronization increases the hardness and reduces the friability of granules. This will reduce the amount of fines generated during handling or transportation.
Dietary Supplement contains only dietary ingredients that are present in the food supply. And the food has not been chemically altered. Chemical alterations are changes in the molecular structure or composition of the ingredients through hydrolysis, distillation, altered production, or fermentation conditions. For example, the use of media containing high levels of sodium selenite can germinate garlic and fermented yeast can produce high levels of organoselenium compounds. Next, we take a look at the summary of the use of Dietary Supplement and their safety profile. Here are some answers.
Here is the content list:
l Summary of the use of Dietary Supplement.
l Demonstrate the safety of Dietary Supplements, otherwise, they will be considered adulterated products.
To a certain extent, the use of Health food has become increasingly common and has influenced the nutritional status of populations. Therefore, the interference of Dietary Supplements should be taken into account when conducting studies on the health effects of nutrients, the efficacy of drugs, and other health-related studies. The possible confounding effects of other user-related behaviors should also be taken into account when evaluating the effects of Dietary Supplements used. In the absence of data on Dietary Supplement use in developed countries, work should be carried out as soon as possible to identify the problem and consider the influencing factors to develop appropriate intervention strategies in China. In addition, the investigation of Dietary Supplements should pay attention to the unification of concepts and methods to facilitate comparison between studies so as to obtain the maximum value of research.
Those who manufacture or distribute the dietary ingredient or Dietary Supplement should provide the Secretary with information that supports their conclusion that the Dietary Supplement containing the dietary ingredient is reasonably expected to be safe, including any references to published research. In other words, if a dietary ingredient intended for use in a Dietary Supplement is not present in the same chemical form in the food supply, an explanation must be given as to why the new dietary ingredient is considered safe for use under the conditions recommended or suggested by the label. If it is uncertain whether a dietary ingredient is a "new dietary ingredient", a notification may still be submitted. Regardless of whether a premarket notification is required, manufacturers and distributors are responsible for assessing the safety of the dietary ingredient used and must ensure that Vitamins sold or distributed are not adulterated. Sales records, sales contracts, manufacturing records, commercial invoices, magazine advertisements, or sales brochures can all be used as evidence to determine whether a dietary ingredient is new.
Our mission is to provide the best possible service to our customers and focus on building long-term partnerships that we believe will lead us to a win-win situation. If you work with Dietary Supplement, you can communicate with us on our website, which is available at https://www.ahchempro.com/.
There is no single product category for our health food products in the USA. Most health food products can be classified as Dietary Supplement or general food with functional claims, and all of them fall within the scope of food regulation. Next, let's take a look at the scope of a Dietary Supplement in the United States and the regulatory authorities. Here are some answers.
Here is the content list:
l The scope of Dietary Supplement in the USA.
l Regulatory authority for Dietary Supplement in the United States.
A Dietary Supplement is a product (not tobacco) intended to supplement the diet and may contain one or more of the following dietary ingredients: vitamins, minerals, herbs (herbal) or other plants, amino acids, and dietary ingredients to increase the total daily intake, or a concentrate, metabolite, extract or combination of these ingredients. It may not be consumed in the form of tablets, capsules, powders, soft gels, or oral liquids; it may not be consumed as a conventional food or as the sole component of a meal diet. DSHEA also allows the use of pharmaceutical ingredients, such as approved or licensed new drugs, antibiotics, biologics, etc., provided that they have been marketed as Immunity increases or food before the relevant approval, certification, or licensing; however, if they have not been marketed as a Dietary Supplement or food before the relevant approval or certification, they may not be used as a Dietary Supplement. However, if the substance has not been marketed as a Dietary Supplement or food before the relevant approval or certification, it may not be used in Dietary Supplement.
The US Food and Drug Administration (FDA), one of the federal executive agencies of the Department of Health and Human Services (HHS), is the regulatory authority for Dietary Supplement, which is different from "conventional" foods and drugs, primarily under DSHEA, which was established in 1994. Dietary Supplements and Dietary Ingredients Manufacturers and distributors of dietary supplements and dietary ingredients are responsible for assessing the safety and labeling of their products before marketing to ensure that they meet all the requirements of DSHEA and the relevant FDA regulations. The Centre for Food Safety and Applied Nutrition (CFSAN) is responsible for the safety and labeling of the Hard capsules. The National Institutes of Health (NIH), one of the HHS divisions, focuses on scientific research and the NIH Office of Dietary Supplement (ODS) coordinates the overall management of the Dietary Supplement. The common goal of NIH and FDA is to promote public health by facilitating the translation of basic and clinical research into medical products and treatments. These agencies complement each other in their roles and functions: NIH supports and conducts biomedical and behavioral research, and FDA ensures the safety and efficacy of medical and other products. In addition, the Committee on Dietary Supplement Labelling (CDSL) examines the regulatory and Dietary Supplement claims on labels and provides recommendations on how best to provide consumers with information that is truthful, scientifically valid, and not misleading. The Commission is composed of seven members appointed by the President. The members of the committee should have expertise and experience in the manufacture, regulation, distribution, and use of Dietary Supplement. At least three of the members should have scientific training and experience to assess the health benefits of Dietary Supplement use, and one of the members should have experience in pharmacology, medical botany, traditional herbal medicine, or other science-related fields. Committee members and staff should be free from bias on Dietary Supplement issues.
If you are interested in a portion of Health food, you can contact us at https://www.ahchempro.com/.
Gout is a type of arthritis. It is caused by having too much of the chemical, uric acid, in your bloodstream. Uric acid is the waste product created when the body breaks down purines a type of protein found in many foods and all of your cells). Increased levels of uric acid in your blood may occur if, for example, your kidneys cannot efficiently remove it, you have a rare genetic abnormality, or because your diet and lifestyle increase the amount of uric acid that you produce. If levels of uric acid are high for prolonged periods, needle-like crystals can start to form in your tissues, resulting in swollen, painful joints.
Your diet plays an important role in both causing gout and reducing the likelihood of suffering further painful attacks of gout. If you already suffer from gout, eating a diet that is rich in purines can result in a five-fold increase in gout attacks.
Fish oil is already a familiar health product. People who are usually busy with work, overuse their brains, middle-aged and elderly can increase their memory, improve their concentration and prevent dementia by taking Fish oil afterward.
This is the list of contents:
·Improves memory
·Protect your eyesight
·Regulates blood lipids
·Cardio-vascular protection
·Prevention of blood clots
·Regulating blood pressure
·Prevents arteriosclerosis
·Boosts the immune system
·Relieves stress
·Relieves joint aches and pains
Fish oil has a brain-boosting effect, by promoting the rapid development of brain cells, it can play a role in improving memory, as well as intellectual decline, forgetfulness, and the effects of dementia. A proper intake of Fish oil in life can effectively help us to increase the DHA content in the brain, which is also helpful for brain cells, whether it is for the elderly or children. When the DHA content is increased, it can promote the nerve health of our brain and allow them to grow and develop at an increased rate. It also provides some relief for our memory and our brain's sensory abilities.
Protect your eyesight
For people who use their eyes a lot, taking Fish oil regularly can help to relieve eye strain and protect your eyesight. Fish oil can provide the DHA needed to reduce the risk of eye disease and eye fatigue because of the large amount of DHA needed in the brain and retina.
Fish oil can reduce the levels of LDL, cholesterol, and triglycerides in the blood. It also provides beneficial HDL, which helps to accelerate the metabolism of saturated fatty acids in the body and prevent the long-term accumulation of fatty acids in the walls of blood vessels.
The substances in Fish oil can effectively control blood lipids, so it is good for cardiovascular protection and can also prevent the development of cardiovascular diseases. Unhealthy eating habits can often lead to an increase in blood lipids, causing a risk of cardiovascular disease. can reduce the risk of angina and heart attacks.
Many people suffer from blood clots and cerebral infarction due to increased blood viscosity, and taking Fish oil can reduce blood viscosity and prevent blood clots, cerebral thrombosis, and cerebral infarction.
High blood pressure is a chronic disease and Fish oil is effective in relieving tension in blood vessels, preventing blood vessel spasms, and regulating blood pressure.
Fish oil has the effect of increasing the elasticity and toughness of blood vessels, so it can be used to inhibit the development of atherosclerosis and prevent the malignant development of the disease.
Fish oil has long been used abroad to treat diabetes, hypertension and rheumatoid arthritis, so regular use of Fish oil can be very helpful in treating these three groups of people.
Fish oil promotes proper blood circulation in the brain, so it can effectively relieve stress in the brain, thus relieving migraines and reducing the frequency of headaches.
Fish oil has anti-inflammatory and anti-swelling properties, which can help to relieve the discomfort caused by arthritis and can significantly reduce joint pain and swelling.
By understanding the advantages of Fish oil, you will have a new understanding of Fish oil, fully illustrating the benefits of eating Fish oil are still relatively large, as long as you choose the regular brand, it is possible to take long-term, very high nutritional value.