Gout is a type of arthritis. It is caused by having too much of the chemical, uric acid, in your bloodstream. Uric acid is the waste product created when the body breaks down purines a type of protein found in many foods and all of your cells). Increased levels of uric acid in your blood may occur if, for example, your kidneys cannot efficiently remove it, you have a rare genetic abnormality, or because your diet and lifestyle increase the amount of uric acid that you produce. If levels of uric acid are high for prolonged periods, needle-like crystals can start to form in your tissues, resulting in swollen, painful joints.
Your diet plays an important role in both causing gout and reducing the likelihood of suffering further painful attacks of gout. If you already suffer from gout, eating a diet that is rich in purines can result in a five-fold increase in gout attacks.
They can be divided in to desired dosage strength without process or formulation changes.
When pellets containing the active ingredient are in the form of suspension, capsules, or disintegrating tablets, they offer significant therapeutic advantages over single unit dosage forms.
They can also be blended to deliver incompatible bioactive agents.
They can also be used to provide different release profile at the same or different sites in the gastrointestinal tract.
Pellets offer high degree of flexibility in the design and development of oral dosage form like suspension,sachet, tablet and capsule.
Pellets disperse freely in gastro intestinal tract (GIT), maximize drug absorption, and minimize local irritation of the mucosa by certain irritant drugs.
Improved flow characteristics: Spheres have excellent flow properties, which can be used in automated processes or in processes where exact dosing is required, e.g. tableting, moulding operations, capsule filling, and packaging.
Coating: Coating of granules is often applied for stabilizing active ingredients in the granule or to control the release of these active ingredients. Typical applications in the pharmaceutical industry are the controlled release medicines. The easiest shape to coat is the sphere due to the absence of edges. It is also the most economical one to coat as no extra coating material is required to fill irregularities in the surface of the granules.
Packing of beds and columns: In certain processes, porous beds or columns are used as chemical reactors. Spherical particles allow the reproduction of beds withalways the same void volume, surface area and permeability. Calculations and predictions of the process characteristics also become easier when round particles are used as many equations are based on flows around symmetrical bodies.
Density increase: Both the true and the bulk density of granules are increased by spheronising. This can improve the process and the packaging.
Marketing: For consumer products, spheronising is sometimes only applied for improved product appearance and marketing reasons.
Hardness and friability: Hardness and friability depend on the internal cohesive forces and surface characteristics. Spheronization increases the hardness and reduces the friability of granules. This will reduce the amount of fines generated during handling or transportation.
There is no single product category for our health food products in the USA. Most health food products can be classified as Dietary Supplement or general food with functional claims, and all of them fall within the scope of food regulation. Next, let's take a look at the scope of a Dietary Supplement in the United States and the regulatory authorities. Here are some answers.
Here is the content list:
l The scope of Dietary Supplement in the USA.
l Regulatory authority for Dietary Supplement in the United States.
A Dietary Supplement is a product (not tobacco) intended to supplement the diet and may contain one or more of the following dietary ingredients: vitamins, minerals, herbs (herbal) or other plants, amino acids, and dietary ingredients to increase the total daily intake, or a concentrate, metabolite, extract or combination of these ingredients. It may not be consumed in the form of tablets, capsules, powders, soft gels, or oral liquids; it may not be consumed as a conventional food or as the sole component of a meal diet. DSHEA also allows the use of pharmaceutical ingredients, such as approved or licensed new drugs, antibiotics, biologics, etc., provided that they have been marketed as Immunity increases or food before the relevant approval, certification, or licensing; however, if they have not been marketed as a Dietary Supplement or food before the relevant approval or certification, they may not be used as a Dietary Supplement. However, if the substance has not been marketed as a Dietary Supplement or food before the relevant approval or certification, it may not be used in Dietary Supplement.
The US Food and Drug Administration (FDA), one of the federal executive agencies of the Department of Health and Human Services (HHS), is the regulatory authority for Dietary Supplement, which is different from "conventional" foods and drugs, primarily under DSHEA, which was established in 1994. Dietary Supplements and Dietary Ingredients Manufacturers and distributors of dietary supplements and dietary ingredients are responsible for assessing the safety and labeling of their products before marketing to ensure that they meet all the requirements of DSHEA and the relevant FDA regulations. The Centre for Food Safety and Applied Nutrition (CFSAN) is responsible for the safety and labeling of the Hard capsules. The National Institutes of Health (NIH), one of the HHS divisions, focuses on scientific research and the NIH Office of Dietary Supplement (ODS) coordinates the overall management of the Dietary Supplement. The common goal of NIH and FDA is to promote public health by facilitating the translation of basic and clinical research into medical products and treatments. These agencies complement each other in their roles and functions: NIH supports and conducts biomedical and behavioral research, and FDA ensures the safety and efficacy of medical and other products. In addition, the Committee on Dietary Supplement Labelling (CDSL) examines the regulatory and Dietary Supplement claims on labels and provides recommendations on how best to provide consumers with information that is truthful, scientifically valid, and not misleading. The Commission is composed of seven members appointed by the President. The members of the committee should have expertise and experience in the manufacture, regulation, distribution, and use of Dietary Supplement. At least three of the members should have scientific training and experience to assess the health benefits of Dietary Supplement use, and one of the members should have experience in pharmacology, medical botany, traditional herbal medicine, or other science-related fields. Committee members and staff should be free from bias on Dietary Supplement issues.
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Children are growing and need more nutrients per kilogram of body weight than adults, but they also have smaller stomachs, which can lead to high demand for nutrients and insufficient intake. At the same time, children are also more prone to picky and fussy eaters and are more prone to nutritional imbalance, so Dietary Supplement is an effective way to regulate their diet. Here are some answers.
Here is the content list:
l Dietary Supplement should not be taken blindly, as it is not a substitute for medication.
l Dietary supplements should not be used as a substitute for daily diet either.
Choose Health food according to its ingredients; follow the label instructions. Do not take it at the same time as similar nutrient supplements to avoid overdose. It is also wrong to forget to take it today and take a double dose tomorrow. Dietary supplements or healthy food should not be taken as a panacea for all diseases. It is not a substitute for medication in the prevention and treatment of disease.
First of all, you should eat a balanced diet and get the necessary nutrients from a balanced diet. Under normal circumstances, if you eat a well-balanced and well-absorbed diet, you will not be deficient in any nutrients and you certainly do not need to take supplements. Some people should take appropriate supplements if for some reason they are poorly absorbed or have increased nutrient requirements. Breastfeeding should be preferred for infants, but vitamin D preparations can be added as appropriate, as breast milk is relatively low in vitamin D. When breastfeeding is not possible for specific reasons, infant formula should be the mainstay, with a gradual transition to a more varied diet; health food is not recommended for infants under 3 years of age. If Dietary Supplement is to be consumed, care should be taken to check the contents of the label under "Unsuitable Groups" and "Precautions".
Children and adolescents should choose Hard capsules based on a balanced diet, adequate exercise, and sufficient sleep, with priority given to essential and easily deficient nutrients, such as vitamins and minerals. For children with a poor appetite, anorexia, growth retardation, short stature, or susceptibility to infections, zinc-rich foods or Dietary Supplements can be used in moderation; for children who do not like to eat vegetables, Dietary Supplement with vitamin C can be used. Ingredients such as deep-sea fish oil, algal oil docosahexaenoic acid, and phosphatidylserine. Or ingredients that can protect the eyes and relieve visual fatigue, such as lingonberry extract, lutein, beta-carotene, etc.
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Fish oil is already a familiar health product. People who are usually busy with work, overuse their brains, middle-aged and elderly can increase their memory, improve their concentration and prevent dementia by taking Fish oil afterward.
This is the list of contents：
·Improves memory
·Protect your eyesight
·Regulates blood lipids
·Cardio-vascular protection
·Prevention of blood clots
·Regulating blood pressure
·Prevents arteriosclerosis
·Boosts the immune system
·Relieves stress
·Relieves joint aches and pains
Fish oil has a brain-boosting effect, by promoting the rapid development of brain cells, it can play a role in improving memory, as well as intellectual decline, forgetfulness, and the effects of dementia. A proper intake of Fish oil in life can effectively help us to increase the DHA content in the brain, which is also helpful for brain cells, whether it is for the elderly or children. When the DHA content is increased, it can promote the nerve health of our brain and allow them to grow and develop at an increased rate. It also provides some relief for our memory and our brain's sensory abilities.
Protect your eyesight
For people who use their eyes a lot, taking Fish oil regularly can help to relieve eye strain and protect your eyesight. Fish oil can provide the DHA needed to reduce the risk of eye disease and eye fatigue because of the large amount of DHA needed in the brain and retina.
Fish oil can reduce the levels of LDL, cholesterol, and triglycerides in the blood. It also provides beneficial HDL, which helps to accelerate the metabolism of saturated fatty acids in the body and prevent the long-term accumulation of fatty acids in the walls of blood vessels.
The substances in Fish oil can effectively control blood lipids, so it is good for cardiovascular protection and can also prevent the development of cardiovascular diseases. Unhealthy eating habits can often lead to an increase in blood lipids, causing a risk of cardiovascular disease. can reduce the risk of angina and heart attacks.
Many people suffer from blood clots and cerebral infarction due to increased blood viscosity, and taking Fish oil can reduce blood viscosity and prevent blood clots, cerebral thrombosis, and cerebral infarction.
High blood pressure is a chronic disease and Fish oil is effective in relieving tension in blood vessels, preventing blood vessel spasms, and regulating blood pressure.
Fish oil has the effect of increasing the elasticity and toughness of blood vessels, so it can be used to inhibit the development of atherosclerosis and prevent the malignant development of the disease.
Fish oil has long been used abroad to treat diabetes, hypertension and rheumatoid arthritis, so regular use of Fish oil can be very helpful in treating these three groups of people.
Fish oil promotes proper blood circulation in the brain, so it can effectively relieve stress in the brain, thus relieving migraines and reducing the frequency of headaches.
Fish oil has anti-inflammatory and anti-swelling properties, which can help to relieve the discomfort caused by arthritis and can significantly reduce joint pain and swelling.
By understanding the advantages of Fish oil, you will have a new understanding of Fish oil, fully illustrating the benefits of eating Fish oil are still relatively large, as long as you choose the regular brand, it is possible to take long-term, very high nutritional value.
Some of the problems faced by food products can be solved by choosing the right form of Fish oil addition and process to ensure oxidative stability, flavor, and uniformity of Fish oil distribution in the product. There are usually 3 forms to choose from pure Fish oil, emulsion, and microencapsulation, and I will introduce you to each of these below.
Here is the list of contents：
·Pure Fish oil
·Emulsions
·Micro-encapsulation
The direct addition of pure Fish oil is not very widely used in food and is suitable for some bread, pure oil-based products (such as vegetable oil), and other products that do not require high uniformity of dispersion but have high requirements for raw material quality, oxidative stability, and flavor.
1. The quality of Fish oil raw materials directly determines its value and application. High-quality Fish oil not only requires its physical and chemical indicators such as acidity, color, and peroxide value to meet a specific range but more importantly, the content of contaminants in it is strictly controlled.
2. Fish oils are highly susceptible to oxidation and the challenge is to improve their stability. The common methods to maintain the stability of Fish oil include protection from light, heat, low temperature, vacuum or nitrogen storage, etc. The addition of antioxidants is more effective and can achieve effective chelation of metal ions and scavenging of oxygen radicals.
1. The emulsion form allows Fish oil to be evenly dispersed in aqueous food systems, with oil-in-water Fish oil emulsions being more widely used in food systems than water-in-oil types. Several factors can affect the stability of Fish oil emulsions. For example, the DHA in Fish oil emulsions adopts a highly protective conformation at the interface against oxidative attack by free radicals and metal ions.
2. The emulsification process generally involves a homogenization process, where both homogenization pressure and temperature have an impact on stability. The effect of temperature on the oxidative stability of Fish oil emulsions is more complex. Temperature affects the actual composition of the Fish oil interface and it is generally accepted that higher temperatures will accelerate oxidation, but increasing the homogenization temperature within a certain range can change the protein conformation.
1. Fish oil microcapsules are powdered Fish oil products made from Fish oil as a core material, which is encapsulated by a specific process using wall materials. This allows the Fish oil to be isolated from the external environment, delaying oxidation, disguising the fishy smell, and greatly improving dispersibility, providing easy access and stable quality raw materials for Fish oil food production.
2. The traditional process of preparing Fish oil microcapsules is mainly emulsification and spray drying. In the preparation process, it is necessary to choose the appropriate wall-to-core ratio and concentration, to ensure that the embedding effect of the premise takes into account the economy. It is also important to note that the larger the particle size of some microcapsules, the more air that may be encapsulated and the more unstable they are. As market demand increases, several new Fish oil microcapsule processing technologies are emerging.
From the above, we know that the three forms of Fish oil addition have their suitable applications and advantages and disadvantages, but basically, they can meet the application needs of different food systems and obtain a product with nutritional value and stability.
Chinese New Year, also known as Spring Festival or the Lunar New Year,
is the festival that celebrates the beginning of a new year on the traditional Chinese calendar.
Hope everything will goes well with everybody in this new year!
